Title: Deep Brain Stimulation for Treatment-Resistant Depression
Recorded on January 16, 2020
Featuring: Paul Holtzheimer, MD
Dr. Holtzheimer is the Deputy for Research at the National Center for Post Traumatic Stress Disorder; and the Associate Professor of Psychiatry and Surgery at the Geisel School of Medicine at Dartmouth and Dartmouth-Hitchcock Medical Center.
Dr. Holtzheimer’s research program focuses on the neurobiology and treatment of mood disorders, primarily using functional and structural neuroimaging (magnetic resonance imaging and electroencephalography) as well as focal neuromodulation (e.g., transcranial magnetic stimulation, transcranial direct current stimulation, and deep brain stimulation).
His clinical and research efforts focus on treatment-resistant mood disorders, brain imaging and brain stimulation therapies, including transcranial magnetic stimulation, electroconvulsive therapy, vagus nerve stimulation, and deep brain stimulation. His clinical research program at Dartmouth aims to better understand the neural circuitry underlying treatment-resistant depression and to use this information to develop and advance novel treatment approaches, with a particular emphasis on brain stimulation therapies..
Deep brain stimulation (DBS) is emerging as a potential intervention for patients with highly treatment-resistant depression (TRD). Early, open-label studies supported the safety and potential efficacy of DBS for TRD but later randomized, controlled trials have yielded mixed results. This presentation will review the history of DBS for TRD, with a specific focus on DBS of the subcallosal cingulate (SCC) – the technique that has been most studied to date. The results of key trials will be critically evaluated, and recent research will be presented that provides a potential direction for further study of this promising intervention.
This webinar is eligible for 1 CE/CME. Read more information on CE/CME here: https://adaa.org/education/ce-credits